Why the study?
Does sTNF-R1 predict mortality in patients with chronic heart failure?
Does sTNF-R1 predict mortality in patients with chronic heart failure?
sTNF-R1 may be a useful biomarker for identifying high-risk chronic heart failure patients and monitoring anti-TNF-alpha treatment.
sTNF-R1 may refine mortality risk stratification in chronic heart failure; leaves open its role in guiding therapy or trials.
sTNF-R1 was the strongest and most accurate prognosticator, independent of established markers of CHF severity. Assessment of sTNF-R1 may be useful in identifying patients who are at high risk of death and in monitoring patients undergoing anti-TNF-alpha treatment.
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Rauchhaus et al. (2000) studied this question.
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