Why the study?
Does aspirin and ticlopidine reduce stent thrombosis in patients after coronary-artery stenting compared to aspirin alone or aspirin plus warfarin?
Does aspirin and ticlopidine reduce stent thrombosis in patients after coronary-artery stenting compared to aspirin alone or aspirin plus warfarin?
Aspirin and ticlopidine is superior to aspirin alone or aspirin plus warfarin for preventing stent thrombosis after coronary stenting, despite an increased risk of bleeding compared to aspirin alone.
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Favors aspirin-ticlopidine over aspirin or aspirin-warfarin post-stenting; confirms dual antiplatelet superiority in RCT evidence.
Leon et al. (1998) studied this question.
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