Incidence and predictors of sudden cardiac death in arrhythmogenic right ventricular cardiomyopathy: a pooled analysis

Figures

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  Figure 1. PRISMA flowchart of study selection. ARVC, arrhythmogenic right ventricular cardiomyopathy; DCM, dilated cardiomyopathy; SCD, sudden cardiac death.

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  Figure 2. Incidence of sudden cardiac death (SCD) in arrhythmogenic right ventricular cardiomyopathy (ARVC). (A) incidence of SCD in ARVC patients with implantable cardioverter-defibrillator (ICD), and (B) incidence of SCD in ARVC patients without ICD. CI, confidence interval; ICD−ve, implantable cardioverter-defibrillator negative; ICD+ve, implantable cardioverter-defibrillator positive; SCD, sudden cardiac death.

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  Figure 3. Incidence rates of aborted SCD and both aborted SCD/SCD in ICD−ve ARVC. (A) incidence of aborted SCD in ARVC patients without ICD, and (B) incidence of both aborted SCD and SCD in ARVC patients without ICD. ARVC, arrhythmogenic right ventricular cardiomyopathy; ICD−ve, implantable cardioverter-defibrillator negative; SCD, sudden cardiac death.

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  Figure 4. Predictors of life-threatening arrhythmic events in ARVC. Life-threatening arrhythmic events were reported as a composite of SCD, aborted SCD, ventricular tachycardia, ventricular fibrillation, appropriate ICD therapy, or cardiovascular death. HR, hazard ratio; ICD, implantable cardioverter-defibrillator; LVEF, left ventricular ejection fraction; NSVT, non-sustained ventricular tachycardia; RV, right ventricular.

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  Figure 5. Incidence of appropriate ICD therapy in ARVC. (A) Overall incidence rate of appropriate ICD intervention in ARVC, and (B) incidence rates of appropriate ICD interventions in ARVC by Task Force Criteria (TFC). ARVC, arrhythmogenic right ventricular cardiomyopathy; ICD, implantable cardiovertr-defibrillator.

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  Figure 6. Predictors of appropriate ICD therapies in ARVC. HR, hazard ratio; ICD, implantable cardioverter-defibrillator; LVEF, left ventricular ejection fraction; NSVT, non-sustained ventricular tachycardia; RV, right ventricular.