Depression and Anxiety as Risk Factors for Morbidity and Mortality After Organ Transplantation

Key Points

• To evaluate the impact of depression and anxiety on clinical morbidity, graft loss, and mortality following organ transplantation.
• Synthesized existing literature evaluating psychological risk factors and their associations with posttransplant morbidity and mortality.
• Depression significantly increases the risk of mortality and graft loss among organ transplant recipients.
• Evidence linking psychiatric distress to broader posttransplant morbidities remains scarce, and whether systematic screening and treatment reduce mortality warrants further investigation.