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April 1, 2026HLA

Identification of the Novel HLA‐B*13:206 Allele by Sanger Dideoxy Sequencing

Caifeng Long Dongmei Li Chengyan Fan Tiecheng Sun Yanjun Jia

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Key Points

The aim is to identify the allele HLA-B*13:206 and understand its genetic variation.
Conducted Sanger dideoxy sequencing of HLA genes.
Focused specifically on codon 194 of exon 4.
Compared HLA-B*13:206 with HLA-B*13:01:01:01.
HLA-B*13:206 was identified with a single nucleotide substitution.
The substitution is located at codon 194 in exon 4.

Implication

Research identifies a new allele HLA-B*13:206 through genetic sequencing, suggesting genetic diversity in human leukocyte antigens.

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Cite This Study

Long et al. (2026) studied this question.

synapsesocial.com/papers/69ddda4de195c95cdefd7c01 https://doi.org/10.1111/tan.70712

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