Why the study?
Does intravenous nicardipine improve haemodynamic indices and serum catecholamine levels compared to nitroprusside in patients with hypertensive crisis and acute pulmonary oedema?
Population
40 patients admitted to the emergency department with a hypertensive crisis and acute pulmonary oedema
Comparison
Intravenous infusion of nicardipine vs Intravenous infusion of nitroprusside
Design
Cohort
Authors
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Supports nicardipine as viable option in hypertensive emergencies; leaves open whether catecholamine effects improve outcomes.
Does intravenous nicardipine improve haemodynamic indices and serum catecholamine levels compared to nitroprusside in patients with hypertensive crisis and acute pulmonary oedema?
Intravenous nicardipine is as effective as nitroprusside for blood pressure reduction in hypertensive emergencies with acute pulmonary edema, with a potentially more favorable effect on sympathetic activation.
HJ et al. (2004) studied this question.
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