Why the study?
Does intravenous nicardipine improve blood pressure control compared to sodium nitroprusside in patients with postoperative hypertension?
Population
139 patients with postoperative hypertension after both cardiac and noncardiac surgery
Comparison
Intravenous nicardipine vs Intravenous sodium nitroprusside
Design
RCT, randomized, open-label
Authors
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Supports preferring nicardipine for rapid postoperative BP control; extends RCT evidence for dihydropyridines over nitroprusside in acute settings.
Does intravenous nicardipine improve blood pressure control compared to sodium nitroprusside in patients with postoperative hypertension?
Intravenous nicardipine is as effective as sodium nitroprusside for postoperative hypertension but achieves blood pressure control more rapidly and with fewer dose adjustments.
Halpern et al. (1992) studied this question.
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