Why the study?
Does isradipine improve blood pressure control compared to sodium nitroprusside in postoperative CABG patients with hypertension?
Population
27 postoperative coronary artery bypass-graft patients with a mean arterial pressure greater than 100 mmHg
Comparison
Isradipine given by infusion vs Sodium nitroprusside given by infusion
Design
RCT, randomized, open
Authors
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Isradipine provides faster, smoother MAP control with less tachycardia than nitroprusside post-CABG; extends options for acute postoperative hypertension.
Does isradipine improve blood pressure control compared to sodium nitroprusside in postoperative CABG patients with hypertension?
Isradipine infusion is an effective and potentially superior alternative to sodium nitroprusside for the acute management of hypertension following CABG surgery.
Lawrence et al. (1993) studied this question.
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