Why the study?
Does nifedipine compared to nitroprusside improve systemic and pulmonary hemodynamics in patients developing acute hypertension during coronary artery bypass surgery?
Population
20 patients undergoing coronary artery bypass grafting who developed acute hypertension
Comparison
Nifedipine (about 3 micrograms kg-1 min-1) vs Nitroprusside (about 0.75 micrograms/kg-1 min-1)
Design
Cohort
Follow-up
intraoperative (about 3 min)
Authors
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Nifedipine may offer distinct hemodynamic effects versus nitroprusside in CABG hypertension; leaves open impact on outcomes without randomized data.
Does nifedipine compared to nitroprusside improve systemic and pulmonary hemodynamics in patients developing acute hypertension during coronary artery bypass surgery?
Nifedipine is an effective vasodilator for controlling intraoperative hypertensive episodes during CABG, primarily affecting systemic resistance vessels without significantly changing venous tone.
Schulte-Sasse et al. (1984) studied this question.
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