Why the study?
Does nifedipine 20 mg administered with premedication improve haemodynamic profiles in patients undergoing elective coronary artery bypass surgery?
Population
40 patients scheduled for elective aortocoronary bypass surgery with normal global left ventricular function
Comparison
Nifedipine 20 mg administered with premedication vs Placebo administered with premedication
Design
RCT, double-blind
Follow-up
Intraoperative
Authors
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Supports nifedipine premedication for hemodynamic optimization before CABG; extends RCT evidence for calcium-channel blockers in cardiac anesthesia.
Does nifedipine 20 mg administered with premedication improve haemodynamic profiles in patients undergoing elective coronary artery bypass surgery?
Nifedipine 20 mg given as premedication before CABG safely reduces systemic vascular resistance and increases cardiac index without causing severe hypotension or adverse anaesthetic interactions.
Christian Meyer (1986) studied this question.
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