What question did this study set out to answer?

This research aims to elucidate the occurrence of fixed drug eruption (FDE) due to mycophenolate mofetil (MMF) in a patient with systemic lupus erythematosus.

April 15, 2026British Journal of Clinical Pharmacology

Fixed drug eruption induced by mycophenolate mofetil, a rare entity with significant consequences

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Authors

CKC. KiefferCentre Hospitalier Universitaire de Rouen MQMathilde QuatremareCentre Hospitalier Universitaire de Rouen OBO. BauvinCentre Hospitalier Universitaire de Rouen

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Implication

Case report reveals mycophenolate mofetil induces fixed drug eruption in a patient, highlighting implications for treatment.

Key Points

This research aims to elucidate the occurrence of fixed drug eruption (FDE) due to mycophenolate mofetil (MMF) in a patient with systemic lupus erythematosus.
Case report of a 52-year-old woman with lupus nephritis experiencing cutaneous reactions to MMF.
Conducted skin prick testing and oral provocation tests to confirm hypersensitivity.
Performed skin biopsy to analyze lesions.
Confirmed delayed hypersensitivity reaction to MMF characterized by recurrent violaceous macules.
Lesions reappeared at identical sites upon re-exposure to MMF during oral provocation testing.
Skin biopsy indicated necrotic keratinocytes and a dermal infiltrate, supporting the FDE diagnosis.

Cite This Study

Kieffer et al. (2026) studied this question.

synapsesocial.com/papers/69df2a4be4eeef8a2a6af797 https://doi.org/10.1002/bcp.70554

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Fixed drug eruption induced by mycophenolate mofetil, a rare entity with significant consequences

Discussion

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Implication

Key Points

Cite This Study

Fixed drug eruption induced by mycophenolate mofetil, a rare entity with significant consequences

Discussion

Member takes

Implication

Key Points

Cite This Study

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