What question did this study set out to answer?

To report unusual rapid onset neutropenia associated with mycophenolate mofetil treatment in two patients.

Rapid Onset Neutropenia After Mycophenolate Mofetil Initiation: 2 Cases

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Case report shows rapid neutropenia after mycophenolate mofetil initiation, suggesting hypersensitivity in patients.

To report unusual rapid onset neutropenia associated with mycophenolate mofetil treatment in two patients.
Case report of two individuals with autoimmune diseases experiencing neutropenia within days of starting MMF.
Monitoring of neutrophil counts post-initiation and upon re-challenge with MMF.
Assessment of prior literature regarding mycophenolate mofetil and side effects.
Case 1: Neutrophils dropped to 0.4 × 10^9/L by day 6 after MMF initiation; resolved post cessation of MMF and filgastrin.
Case 2: Neutrophils fell from 11.1 × 10^9/L to 2.4 × 10^9/L within 4 days; normalization occurred after holding MMF and later re-initiated despite recurrence of neutropenia.

Hitchman et al. (2026) studied this question.

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