Population
Class II myosins / muscle thick filaments
Design
Review
Authors
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May guide cardiac muscle regulation insights; leaves open therapeutic targeting of myosin off-states in disease.
This review highlights the conserved structural motifs, such as head-head and head-rod interactions, that regulate the inactive state of divergent class II myosins across species.
Lowey et al. (2010) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: