Comparative analysis demonstrates depleted Faecalibacterium prausnitzii in patients with inflammatory bowel disease, suggesting its essential role in maintaining gut mucosal protection.
The fecal microbiota of patients with IBD differs from that of HS. The phylum Firmicutes and particularly the species F. prausnitzii, are underrepresented in A-IBD patients as well as in IC patients. These bacteria could be crucial to gut homeostasis since lower counts of F. prausnitzii are consistently associated with a reduced protection of the gut mucosa.
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Sokol et al. (2009) studied this question.
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