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This research aims to develop and evaluate a dual electrochemical sensor for quantifying ascorbic acid and uric acid.

April 17, 2026Analytical SciencesOpen Access

Dual electrochemical sensor based on graphene aerogel for quantification of ascorbic acid in pharmaceutical samples and uric acid in urine

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This work demonstrates a dual electrochemical sensor quantifying ascorbic acid and uric acid, suggesting effective detection in various samples.

This research aims to develop and evaluate a dual electrochemical sensor for quantifying ascorbic acid and uric acid.
Modification of glassy carbon electrodes with graphene aerogel dispersed in polyethylenimine.
Detection of ascorbic acid and uric acid using differential pulse voltammetry.
Evaluation of sensitivity, linear response, and minimum detection concentrations.
Sensitivity for ascorbic acid is approximately 2.13 × 10^4 µAM−1 and for uric acid is 5.0 × 10^4 µAM−1.
Linear range for ascorbic acid is from 1.0 to 10 × 10−4 M with a minimum detection concentration of 0.25 µM.
Linear range for uric acid is from 1.0 to 15.0 × 10−5 M with a minimum detection concentration of 9 µM.

Gutiérrez et al. (2026) studied this question.

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This work demonstrates a dual electrochemical sensor quantifying ascorbic acid and uric acid, suggesting effective detection in various samples.