Key result
WiSE-CRT combined with AVEIR enables fully leadless biventricular pacing for patients failing conventional CRT.
Why the study?
Conventional CRT can be limited by anatomical or technical constraints or non-response, prompting evaluation of fully leadless pacing systems such as combining WiSE-CRT with the AVEIR platform.
The combination of the WiSE-CRT system with the AVEIR VR leadless pacemaker is a feasible and effective fully leadless biventricular pacing strategy for patients who are non-responders to conventional CRT.
Broadens leadless CRT options for patients limited by anatomy or technical constraints; extends prior WiSE-Micra experience to AVEIR.
Key Teaching Points The WiSE-CRT system provides a viable alternative for patients who are non-responders to conventional CRT Fully leadless pacing systems are emerging as valuable alternatives for patients in whom conventional CRT is limited by anatomical or technical constraints, offering new solutions for complex clinical scenarios. The combination of WiSE-CRT with the AVEIR platform expands the potential of leadless biventricular pacing beyond the previously described WiSE-Micra experience.
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Marino et al. (2026) studied this question. The combination of WiSE-CRT with the AVEIR platform expands fully leadless biventricular pacing as a viable alternative for patients limited by or non-responsive to conventional CRT.
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