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April 21, 2026SHILAP Revista de lepidopterologíaOpen Access

Elevated ApoC3 levels in cerebrospinal fluid predict poor outcomes in patients with aneurysmal subarachnoid hemorrhage

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Authors

BTBin TongYWYì WángJCJiarui Chen

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Overview

Study reveals that elevated ApoC3 levels predict poor outcomes in aneurysmal subarachnoid hemorrhage, suggesting a potential biomarker for complications.

Key Points

  • This research aims to determine if ApoC3 levels in cerebrospinal fluid can predict complications in patients with aneurysmal subarachnoid hemorrhage.
  • Enrolled 63 patients with aneurysmal subarachnoid hemorrhage.
  • Performed ELISA analysis on cerebrospinal fluid samples to assess ApoC3 levels.
  • Evaluated predictive value using receiver operating characteristic curve analysis.
  • Elevated ApoC3 levels in cerebrospinal fluid were significantly associated with worse 3-month functional outcomes.
  • Patients with ApoC3 levels above 4,463 ng/mL had a higher incidence of delayed cerebral ischemia and hydrocephalus.
  • Increased ApoC3 concentrations correlated with an elevated risk of severe complications.

Cite This Study

Tong et al. (2026) studied this question.

synapsesocial.com/papers/69e7132bcb99343efc98cef7https://doi.org/10.3389/ebm.2026.10827
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  5. 5Association of Serial Ventricular Routine Cerebrospinal Fluid Findings with Complications and Outcome in Aneurysmal Subarachnoid Hemorrhage: A Retrospective Observational Study2025