Flattening of the mitral annular saddle shape observed on 3D echocardiography is linked to leaflet billowing and chordal rupture, contributing to mitral regurgitation in prolapse.
Flattening of the annular saddle shape is associated with progressive leaflet billowing and increased frequencies of chordal rupture and may be important in the pathogenesis of MR in mitral valve prolapse.
Lee et al. (Tue,) studied this question.