Population
Numerical mitral annular phantoms and experimental data from 3 humans, 5 sheep, and 2 baboons
Comparison
Saddle-shaped mitral annulus vs Flat mitral annulus
Design
Preclinical
Authors
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Supports saddle-shaped mitral annuloplasty to reduce leaflet stress; animal data leaves clinical translation open.
The saddle shape of the mitral annulus reduces mechanical stress on the leaflets, which may inform the design of future mitral annular prostheses.
Salgo et al. (2002) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: