Visible-Light-Driven Manganese-Catalyzed Bromination Reactions with Dibromomethane

An efficient visible-light-induced manganese-catalyzed system has been established for bromination by using dibromomethane as the brominating reagent. This protocol enables diverse bromination reactions, including bromination of arenes, α-selective bromination of cinnamaldehydes, and benzylic C(sp³)-H bromination. These reactions proceed under photosensitizer-free and mild reaction conditions. Consequently, this methodology provides a novel and environmentally benign strategy for the synthesis of brominated compounds.