El índice de triglicéridos y glucosa y su utilidad en la práctica clínica como herramienta de evaluación del riesgo cardiovascular

Q: What is the clinical evidence from this study?

Study design: Editorial. Population: Cardiovascular risk and insulin resistance. Intervention: Triglyceride-Glucose (TyG) index.

Q: What does this research mean for the field?

The Triglyceride-Glucose index serves as a simple, reproducible, and low-cost indirect marker of insulin resistance for assessing cardiovascular risk in routine clinical practice. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

Héctor Martínez-Ruiz; Nayelli Nájera; Guillermo Ceballos

doi:10.35366/122887

January 1, 2026Cardiovascular and Metabolic ScienceOpen Access

El índice de triglicéridos y glucosa y su utilidad en la práctica clínica como herramienta de evaluación del riesgo cardiovascular

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Key Points

Evaluate the clinical utility of the triglyceride-glucose (TyG) index as an accessible, cost-effective surrogate marker of insulin resistance and cardiovascular risk in primary care.
Reviewed literature evaluating the TyG index, defined by the formula Ln [fasting triglycerides (mg/dL) × fasting glucose (mg/dL)]/2.
Assessed TyG prognostic utility against standard insulin resistance evaluation tools, including the euglycemic clamp, HOMA-IR, and QUICKI.
Elevated TyG index values greater than 4.91 demonstrate high predictive capacity for the development of hypertension.
Higher TyG values associate with elevated risk for major adverse cardiovascular events, cerebrovascular events, and all-cause mortality after adjustment for traditional cardiovascular risk factors.

PICO

P

Population

Cardiovascular risk and insulin resistance

I

Intervention / Comparator

Triglyceride-Glucose (TyG) index

Limitations

The TyG index is an indirect marker and is not intended to replace more complex methods like the euglycemic clamp.

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Implication

The TyG index is highlighted as a simple, reproducible, and low-cost surrogate marker for insulin resistance to assess cardiovascular risk in routine clinical practice.

Abstract

The triglyceride-glucose index and its usefulness in clinical practice as a cardiovascular risk assessment tool El ndice de triglicridos y glucosa y su utilidad en la prctica clnica como herramienta de evaluacin del riesgo cardiovascular

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Cite This Study

Martínez-Ruiz et al. (2026) conducted an editorial in Cardiovascular risk and insulin resistance. Triglyceride-Glucose (TyG) index was evaluated.

synapsesocial.com/papers/69ec593e88ba6daa22dab44a https://doi.org/10.35366/122887

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El índice de triglicéridos y glucosa y su utilidad en la práctica clínica como herramienta de evaluación del riesgo cardiovascular

Key Points

PICO

Limitations

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

El índice de triglicéridos y glucosa y su utilidad en la práctica clínica como herramienta de evaluación del riesgo cardiovascular

Key Points

PICO

Limitations

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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