Why the study?
Cardiac allograft vasculopathy is a leading cause of mortality after heart transplantation, and optical coherence tomography was used to study the development of healed coronary plaques.
Optical coherence tomography identifies healed coronary plaques as the predominant early de novo lesion in cardiac allograft vasculopathy after heart transplantation.
Cardiac allograft vasculopathy (CAV) is a leading cause of mortality after heart transplant (HTx). High-resolution intravascular imaging with optical coherence tomography (OCT) enables early detection and plaque characterization, with prior studies suggesting healed coronary plaques (HCPs), a layered plaque morphology, as the predominant lesion type. We used OCT to study HCP development after HTx.
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Monia et al. (2026) studied this question.
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