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Review highlights the impact of type 2 diabetes on multiple myeloma outcomes, suggesting implications for patient care.
There is a clear link between type 2 diabetes mellitus (DM) and overall cancer risk. However, studies evaluating type 2 DM and multiple myeloma (MM) risk are limited, and the association is less clear. Understanding the impact of longstanding type 2 DM on organ systems and symptomatology in patients with a subsequent MM diagnosis, alongside potential overlapping toxicities from MM treatment, is crucial. This review summarizes the role of type 2 DM on MM risk and outcomes and explores the various mechanisms underlying these associations. A better understanding of this association will help improve outcomes in diabetic MM patients through lifestyle and drug related interventions. Clinical trial registration: Not applicable.
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Parikh et al. (2026) studied this question.
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