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Comparative evaluation demonstrates increased delayed healing and inflammation in overlapping drug-eluting stents, indicating a need for closer patient monitoring.
Compared with bare metal stents, drug-eluting stents further delay arterial healing and promote inflammation at sites of overlap. Taxus stents induced greater fibrin deposition, medial cell loss, heterophils/eosinophils, and late neointimal hyperplasia. Patients receiving overlapping drug-eluting stents need more frequent follow-up than patients with nonoverlapping stents.
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Finn et al. (2005) studied this question.
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