Shows impaired renal function predicts mortality in chronic heart failure, implying importance of renal monitoring.
Impaired renal function (GFR(c)) is a stronger predictor of mortality than impaired cardiac function (LVEF and New York Heart Association class) in advanced CHF, and it is associated with increased levels of N-terminal ANP. Moreover, impaired renal function was not related to LVEF, which suggests that factors other than reduced cardiac output are causally involved.
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Hillege et al. (2000) studied this question.
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