Key result
Home-based telerehabilitation matches center-based cardiac rehab in reducing anxiety and depression after CABG.
Why the study?
Psychological distress and reduced quality of life are common after CABG, but access barriers limit participation in traditional center-based cardiac rehabilitation.
Does a home-based telerehabilitation program improve anxiety, depression, and quality of life compared to center-based cardiac rehabilitation or usual care in post-CABG patients?
RCT (n=110)
Single-blind (outcome assessors and data analysts blinded)
1:1:1 ratio via computer-based program
No
Does a home-based telerehabilitation program improve anxiety, depression, and quality of life compared to center-based cardiac rehabilitation or usual care in post-CABG patients?
Effect estimate: Mean difference -0.4 (95% CI -1.8 to 1.0)
Absolute Event Rate: -8.3% vs -7.9%
p-value: p=0.58
Home-based telerehabilitation is as effective as traditional center-based cardiac rehabilitation in reducing anxiety and depression and improving quality of life after CABG, offering a viable alternative to overcome participation barriers.
Supports HBTCR to broaden CR access post-CABG; confirms comparable efficacy to CBCR for anxiety reduction.**[[1]](https://link.springer.com/article/10.1186/s12872-026-05703-1)[[2]](https://clinicaltrials.
Anxiety, depression, and reduced quality of life are common after coronary artery bypass grafting (CABG), yet participation in traditional center-based cardiac rehabilitation (CBCR) is limited by access barriers. This study aims to compare the effectiveness of a home-based telerehabilitation (HBTCR) program with CBCR in improving psychological and quality-of-life outcomes for post-CABG patients. In this prospective randomized controlled trial, 110 clinically stable patients 4–8 weeks post-CABG were allocated to a 12-week HBTCR program (wearable monitoring, mobile app, weekly nurse support), CBCR (supervised center sessions), or usual care. Primary outcomes were changes in Hamilton Anxiety (HAMA) and Depression (HAMD-17) scores. The secondary outcome was change in health-related quality of life (SF-36). Both HBTCR and CBCR groups demonstrated significant and comparable improvements compared to usual care (mean HAMA change: -8.3 vs. -7.9 vs. -1.1, P < 0.001; HAMD-17: -9.5 vs. -9.1 vs. -1.5, P < 0.001). No significant difference was found between HBTCR and CBCR. Quality of life improved significantly across all SF-36 domains in both intervention groups versus control (P < 0.01). A structured home-based telerehabilitation program is as effective as traditional center-based rehabilitation in alleviating psychological distress and enhancing quality of life after CABG. HBTCR represents a vital, accessible alternative to deliver comprehensive cardiac rehabilitation and overcome participation barriers. This trial was retrospectively registered at ClinicalTrials.gov (identifier: NCT07232693, Registration date: 2025-11-14).
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Y et al. (2026) conducted an RCT in Post-Coronary Artery Bypass Grafting (CABG) (n=110). Home-based telerehabilitation (HBTCR) vs. Center-based cardiac rehabilitation (CBCR) and usual care was evaluated on Change in Hamilton Anxiety Scale (HAMA) score from baseline (Mean difference -0.4, 95% CI -1.8 to 1.0, p=0.58). Home-based telerehabilitation was as effective as center-based cardiac rehabilitation in reducing anxiety (mean difference -0.4) and depression after coronary artery bypass grafting.
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