August 29, 2008
View Full PaperLong Term Vagal Stimulation in Patients with Advanced Heart Failure First Experience in Man
Structured PICO
Is long term vagal stimulation feasible, safe, and effective in patients with advanced heart failure?
P
Population
Patients with advanced heart failure
I
Intervention
Long term vagal stimulation
O
Outcome
Feasibility, safety, tolerability, and preliminary efficacysafety
Long-term vagal stimulation represents a feasible and safe novel approach for advanced heart failure, with promising preliminary efficacy that warrants larger multicenter trials.
Abstract
This novel approach to the treatment of patients with HF is feasible, and appears safe and tolerable. The preliminary efficacy results appear promising. These findings suggest the opportunity to proceed with a larger multicentre study.