Arrhythmogenic mitral valve prolapse syndrome with sudden cardiac arrest is characterized by young female patients with bileaflet prolapse, mitral annular disjunction, and specific ECG abnormalities.
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Supports risk stratification in mitral valve prolapse; leaves open prospective validation and intervention trials.
In this international descriptive registry of patients with arrhythmogenic mitral valve prolapse syndrome and SCA, patients were young, women, and had bileaflet mitral valve prolapse, mitral annular disjunction, inferolateral T-wave inversions, and nonsustained VT. A history of syncope and anterolateral T-wave inversions was relatively common in patients who survived SCA or sustained VT/ventricular fibrillation.
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Chakrabarti et al. (2025) studied this question.
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