Why the study?
Does serum PIP concentration correlate with myocardial collagen content in patients with essential hypertension?
Does serum PIP concentration correlate with myocardial collagen content in patients with essential hypertension?
Serum PIP concentration may serve as an easy and reliable biomarker for screening and diagnosing severe myocardial fibrosis in patients with arterial hypertension.
Serum PIP may indicate myocardial fibrosis in hypertension; hypothesis-generating and requires prospective validation before clinical adoption.
These results show a strong correlation between myocardial collagen content and the serum concentration of PIP in essential hypertension. Although preliminary, these findings suggest that the determination of PIP may be an easy and reliable method for the screening and diagnosis of severe myocardial fibrosis associated with arterial hypertension.
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Querejeta et al. (2000) studied this question.
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