Why the study?
Does early surgery reduce cardiac mortality and congestive heart failure hospitalization compared to conservative management in asymptomatic patients with severe degenerative mitral regurgitation?
Does early surgery reduce cardiac mortality and congestive heart failure hospitalization compared to conservative management in asymptomatic patients with severe degenerative mitral regurgitation?
Early surgery is associated with decreased cardiac mortality and heart failure hospitalization compared to conservative management in asymptomatic patients with severe degenerative mitral regurgitation.
Does not support practice change for asymptomatic severe degenerative MR; leaves open benefit of early surgery pending randomized data.
Compared with conservative management, the strategy of early surgery was associated with an improved long-term event rate by decreasing cardiac mortality and congestive heart failure hospitalization more effectively in patients with severe degenerative mitral regurgitation. Early surgery may therefore further improve clinical outcomes in asymptomatic severe mitral regurgitation with preserved left ventricular systolic function and a high likelihood of mitral valve repair.
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Kang et al. (2009) studied this question.
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