What is the clinical and prognostic impact of persistent microvascular obstruction in CMR after reperfused STEMI?
Persistent microvascular obstruction after reperfused STEMI is an adverse prognostic marker associated with larger infarcts, intramyocardial hemorrhage, and major adverse cardiac events.
Persistent MVO after STEMI occurs in up to 10% of patients with baseline MVO and is linked to major adverse cardiac events. Patients with MVO persistence had larger infarcts, lower left ventricular function, and more frequent intramyocardial hemorrhage at baseline CMR. All patients with MVO persisting ≥12 months initially showed intramyocardial hemorrhage.
Troger et al. (Tue,) studied this question.