Why the study?
Does high-sensitivity ST2 improve the prediction of adverse outcomes in patients with chronic heart failure?
Does high-sensitivity ST2 improve the prediction of adverse outcomes in patients with chronic heart failure?
High-sensitivity ST2, particularly when combined with NT-proBNP, provides incremental prognostic value over standard clinical risk scores in chronic heart failure.
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Should not yet change risk assessment in chronic HF; leaves open whether ST2 integration improves decision-making or outcomes.
ST2 is a potent marker of risk in chronic heart failure and when used in combination with NT-proBNP offers moderate improvement in assessing prognosis beyond clinical risk scores.
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Ky et al. (2010) studied this question.
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