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Prognostic value of apoptosis markers in advanced heart failure patients | Synapse

December 9, 2008European Heart Journal112 citationsOpen Access

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Prognostic value of apoptosis markers in advanced heart failure patients

ANAlexander Niessner PHPhilipp J. Hohensinner KRKathrin Rychli

Structured PICO

Do apoptosis markers (sFAS, sTRAIL) predict risk in advanced heart failure patients?

P

Population

Advanced heart failure patients

I

Intervention

Measurement of apoptosis markers (sFAS, sTRAIL)

O

Outcome

Prognosis/risk prediction

sFAS and sTRAIL may serve as useful prognostic biomarkers in advanced heart failure, with sFAS predicting risk and sTRAIL appearing protective.

Abstract

sFAS is an independent risk predictor in advanced HF patients. It may be of particular value for the identification of high-risk patients in addition to BNP. Conversely, sTRAIL appears to be protective and could be an interesting therapeutic agent.

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Cite This Study

Niessner et al. (Tue,) studied this question.

synapsesocial.com/papers/69effb6cafa91c76b5d0a8ab https://doi.org/https://doi.org/10.1093/eurheartj/ehp004