What question did this study set out to answer?

Evaluate the association between surgical delay greater than 8 hours and postoperative complications in complicated acute appendicitis.

Time to Surgery and Postoperative Complications in Complicated Acute Appendicitis: An Ambispective Cohort Study

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Ambispective cohort study evaluates surgical delay effects on postoperative complications in adults, suggesting delay increases risk.

Evaluate the association between surgical delay greater than 8 hours and postoperative complications in complicated acute appendicitis.
Ambispective cohort study conducted at a high-complexity referral hospital from January 2019 to March 2023.
Included 364 adult patients with histopathologically confirmed complicated acute appendicitis, divided by surgical delay of 8 hours or less versus greater than 8 hours.
Compared postoperative complications during hospitalization between the two groups and calculated relative risks with confidence intervals.
Postoperative complications were higher in patients with surgical delays over 8 hours (15.38%) compared to those operated within 8 hours (3.85%), with RR 4.00, 95% CI 1.82–8.80, p < 0.001.
Increased surgical site infections were noted with delays (7.69% vs 1.65%; RR 4.66, 95% CI 1.36–15.98).
Higher rates of intra-abdominal abscesses (8.24% vs 1.65%; RR 4.99, 95% CI 1.48–16.86) and surgical reintervention (10.99% vs 3.85%; RR 2.86, 95% CI 1.24–6.58) were also observed.

Araujo-Zelada et al. (2026) studied this question.

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