Key result
An in-hospital delay of over 12 hours before laparoscopic appendicectomy for acute appendicitis was not significantly associated with delayed hospital discharge (OR 1.05, p=0.823).
Why the study?
Urgent surgery is sometimes postponed until morning due to diminished nighttime operating capacity, but whether a delay of over 12 hours in laparoscopic appendicectomy for acute appendicitis worsens patient outcomes remained unclear.
Does a delay in laparoscopic appendicectomy >12 hours increase delayed discharge in patients with acute appendicitis?
Cohort (n=446)
No
Does a delay in laparoscopic appendicectomy >12 hours increase delayed discharge in patients with acute appendicitis?
Odds Ratio: 1.05
Absolute Event Rate: 70.1% vs 72.3%
p-value: p=0.823
A short in-hospital delay (>12 hours) for laparoscopic appendicectomy does not significantly increase the risk of delayed discharge or postoperative complications in patients with acute appendicitis.
No association with delayed discharge should not alter appendicectomy timing; leaves open need for randomized confirmation of safe thresholds.
Background and objective In many hospitals, the availability of operating theatres and access to senior surgical and anaesthetic support diminish during night hours. Therefore, urgent surgery is sometimes postponed until the following morning rather than performed overnight, if it is judged to be safe. In this study, we aimed to determine if a delay in laparoscopic appendicectomy in cases of acute appendicitis of over 12 hours, analogous to an overnight delay, correlated with worse patient outcomes. Our primary outcome was delayed discharge from the hospital. Our secondary outcomes were appendicitis severity, conversions, and postoperative complications. Methods We undertook a retrospective review of the medical records of patients who underwent laparoscopic appendicectomy for appendicitis at a UK district general hospital between 01/01/2018 and 30/08/2019. For each patient, clinical and demographic information, and time of hospital admission, surgery, and discharge were collected. Delayed discharge was defined as "time to discharge" >24 hours after surgery. Results A total of 446 patients were included in the study. In 137 patients (30.7%), "time to surgery" was under 12 hours; in 309 patients (69.3%) "time to surgery" was over 12 hours. Of note, 319 patients (71.5%) had a delayed discharge; 303 patients (67.9%) had complicated appendicitis, and 143 patients had severe appendicitis (32.1%). No statistically significant association between "time to surgery" and delayed discharge, appendicitis severity, conversion, or 30-day re-presentations was observed. Conclusion Time from admission to the start of appendicectomy did not affect patient outcomes. Short in-hospital delays in appendicectomy, such as an overnight delay, may be safe in certain patients and should be determined based on clinical judgement.
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Claydon et al. (2022) conducted a cohort in Acute appendicitis (n=446). Time to surgery >12 hours vs. Time to surgery <12 hours was evaluated on Delayed discharge from the hospital (time to discharge >24 hours after surgery) (OR 1.05, p=0.823). An in-hospital delay of over 12 hours before laparoscopic appendicectomy for acute appendicitis was not significantly associated with delayed hospital discharge (OR 1.05, p=0.823).
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