Key result
Delaying an appendectomy for >6 hours from surgical diagnosis did not significantly increase the 30-day complication rate compared to early surgery (≤6 hours) (6.8% vs 5.9%; P=0.93).
Why the study?
Does delaying an appendectomy >6 hours increase complications or length of stay in patients undergoing appendectomy?
Population
342 patients who underwent an appendectomy from January 2009 to December 2010
Comparison
Late appendectomy vs Early appendectomy
Design
Cohort
Follow-up
30-day
Authors
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Supports scheduling flexibility up to 24 hours; hypothesis-generating and requires randomized confirmation.
Cohort (n=342)
No
Does delaying an appendectomy >6 hours increase complications or length of stay in patients undergoing appendectomy?
Absolute Event Rate: 6.8% vs 5.9%
p-value: p=0.93
Delaying an appendectomy more than 6 hours, but less than 24 hours from diagnosis, appears safe and does not lead to worse outcomes.
Nagpal et al. (2012) conducted a cohort in Appendicitis (n=342). Delaying appendectomy >6 hours vs. Early appendectomy (≤6 hours delay) was evaluated on 30-day complication rate (p=0.93). Delaying an appendectomy for >6 hours from surgical diagnosis did not significantly increase the 30-day complication rate compared to early surgery (≤6 hours) (6.8% vs 5.9%; P=0.93).
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