Extent and Direction of Arterial Remodeling in Stable Versus Unstable Coronary Syndromes
Why the study?
Does the extent and direction of arterial remodeling differ between patients with unstable versus stable coronary syndromes?
Population
131 patients undergoing intravascular ultrasound before coronary intervention
Comparison
Unstable coronary syndromes vs Stable coronary syndromes
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
Arterial remodeling patterns differ by lesion stability on IVUS; leaves open prospective validation before informing clinical risk stratification.
Structured PICO
Does the extent and direction of arterial remodeling differ between patients with unstable versus stable coronary syndromes?
P
Population
131 patients (85 with unstable and 46 with stable coronary syndromes) undergoing intravascular ultrasound before coronary intervention
I
Intervention
Unstable coronary syndromes
C
Comparator
Stable coronary syndromes
O
Outcome
Arterial remodeling (remodeling ratio, plaque area, external elastic membrane area, and frequency of positive/negative remodeling)surrogate
Positive arterial remodeling and larger plaque areas on intravascular ultrasound are associated with unstable coronary syndromes, whereas negative remodeling is more common in stable presentations.
Cite This Study
Schoenhagen et al. (2000) studied this question.