Key result
CHA2DS2-VASc score 1 subgroups show similar arterial thromboembolism risk with no significant difference.
Why the study?
Does the risk of arterial thromboembolism differ between patients with atrial fibrillation and CHA2DS2-VASc score 1 versus score 2?
Cohort
Yes
Does the risk of arterial thromboembolism differ between patients with atrial fibrillation and CHA2DS2-VASc score 1 versus score 2?
Answers are grounded in this paper and cite their sources.
Patients with atrial fibrillation and CHA2DS2-VASc score 1 have a similar risk of arterial thromboembolism to those in the intermediate risk group, supporting current recommendations.
Female sex was not considered a risk factor in any risk group. The outcome was arterial thromboembolism (ischemic stroke, embolism of extremity, or transient cerebral ischemia). Study groups were compared using Cox regression analysis. RESULTS: =0.15 for difference). These findings support current recommendations that patients within this intermediate risk group could be identified with a similar risk of arterial thromboembolism.
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Østergaard et al. (2023) conducted a cohort in Atrial fibrillation. CHA2DS2-VASc score 1 subgroups vs. CHA2DS2-VASc score 0 or 2 (age >=75 years without other risk factors) was evaluated on Arterial thromboembolism (ischemic stroke, embolism of extremity, or transient cerebral ischemia) (p=0.15 for difference). CHA2DS2-VASc score 1 subgroups had a similar risk of arterial thromboembolism without a significant difference between groups (P=0.15 for difference).
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