This synthesis method demonstrates selective formation of quinoline derivatives in a novel cyclization, indicating a significant advancement in organic chemistry.
A transition-metal-free [2+4] cyclization reaction of benzothiazolium salts with 2-aminobenzaldehydes has been developed, enabling the selective synthesis of N-substituted and S-substituted quinoline derivatives. The chemoselectivity is primarily controlled by the...
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Chen et al. (2026) studied this question.
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