April 1, 1993Radiology
Left ventricular measurements with cine and spin-echo MR imaging: a study of reproducibility with variance component analysis.
Why the study?
Is there a difference in the reproducibility of left ventricular measurements between cine and spin-echo MR imaging?
Population
40 serial MR imaging examinations
Comparison
Cine magnetic resonance (MR) imaging vs Spin-echo magnetic resonance (MR) imaging
Authors
Discussion
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Member takes
Implication
Variability estimates guide detection of true LV change on MRI; leaves open technique selection for serial monitoring.
Key Points
- To evaluate and compare the reproducibility of left ventricular volume, mass, and wall stress measurements obtained via cine and spin-echo magnetic resonance imaging using variance component analysis.
- Two observers analyzed 40 serial MRI examinations twice each, yielding a dataset of 160 repeated measurements.
- Quantified intraobserver, interobserver, and interexamination errors for cine and spin-echo MRI protocols using variance component analysis.
- Estimated 95% ranges for detectable change were 10% vs. 12% for ejection fraction, 16% vs. 21% for wall mass, and 22% vs. 20% for wall stress in cine vs. spin-echo MRI, respectively.
- Reproducibility did not differ significantly between cine and spin-echo MRI modalities.
- Interexamination variability represented the single largest contributor to total measurement variance across parameters.
Structured PICO
Is there a difference in the reproducibility of left ventricular measurements between cine and spin-echo MR imaging?
P
Population
40 serial MR imaging examinations
I
Intervention
Cine magnetic resonance (MR) imaging
C
Comparator
Spin-echo magnetic resonance (MR) imaging
O
Outcome
Reproducibility of repeated measurements of left ventricular volumes, weight, and wall stresssurrogate
Both cine and spin-echo MR imaging provide highly reproducible measurements of left ventricular volumes, mass, and wall stress, with interexamination variability being the main source of variance.
Cite This Study
Pattynama et al. (1993) studied this question.