What question did this study set out to answer?

Synthesize evidence on pulse pressure amplification and evaluate the clinical significance of measuring central versus brachial blood pressure in arterial hypertension.

June 30, 2009Hypertension

Role of Pulse Pressure Amplification in Arterial Hypertension

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Design

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Authors

AAAlberto AvolioVascular Medicine LBLuc M. Van BortelVascular Medicine PBPierre BoutouyrieVascular Medicine

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Implication

Central BP may refine risk stratification in hypertension; leaves open effects on outcomes or treatment decisions.

Key Points

Synthesize evidence on pulse pressure amplification and evaluate the clinical significance of measuring central versus brachial blood pressure in arterial hypertension.
Reviewed updated European Society of Hypertension guidelines incorporating aortic stiffness and central hemodynamics as target organ damage indices.
Synthesized consensus recommendations and pathophysiological data on pressure wave amplification and noninvasive central hemodynamic assessment.
Systolic blood pressure and pulse pressure differ markedly between the brachial artery and central aorta due to pulse pressure amplification.
Antihypertensive medications produce disparate effects on central versus peripheral pressures, with central hemodynamics correlating more strongly with cardiovascular events.

Cite This Study

Avolio et al. (2009) studied this question.

synapsesocial.com/papers/69f29d4a1b51e2fbf0187509 https://doi.org/10.1161/hypertensionaha.109.134379

Topics

Hypertension management

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Role of Pulse Pressure Amplification in Arterial Hypertension

Discussion

Member takes

Implication

Key Points

Cite This Study

Topics

Role of Pulse Pressure Amplification in Arterial Hypertension

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Topics

Also Consider