Relationship between Violation of Global Meaning and Clinical Symptoms during the COVID-19 Pandemic: A Three-Pathway Model

= 1106 adults. The results suggest that the violation of schemas affects depression and anxiety symptoms through three pathways: (a) Path one, directly, schema violation explains clinical symptoms; (b) Path two, indirectly, schema violation explains clinical symptoms through the search for meaning and negative effect; and (c) Path three, the presence of meaning explains positive affect and buffers clinical symptoms. The three-pathway model explains 90% of the variance in clinical symptoms. The three-pathway model has clinical implications for the assessment, prevention, and treatment of people who are coping with unforeseen negative situations.