Why the study?
The long-term effect of ventricular pacing on myocardial perfusion and function in humans is unclear, although animal studies suggested potential adverse effects.
Does long-term right ventricular apical pacing affect myocardial perfusion and left ventricular function in patients with complete heart block?
Population
43 patients with complete heart block and DDDR pacing
Design
Cross-sectional study
Authors
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Should not yet alter RV pacing site selection in AV block; leaves open long-term clinical impact of observed perfusion and functional changes.
Does long-term right ventricular apical pacing affect myocardial perfusion and left ventricular function in patients with complete heart block?
Long-term right ventricular apical pacing is associated with a high incidence of myocardial perfusion defects, which correlate with impaired global left ventricular function and apical wall motion abnormalities.
Tse et al. (1997) studied this question.
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