Overview of Stent Thrombosis: Mechanisms and Clinical Implications

Stent thrombosis (ST) is a major complication after percutaneous coronary intervention. There have been many basic research and clinical studies to identify the exact pathophysiology of ST and also, many efforts were made to overcome and to prevent this catastrophic event which is associated with desperate clinical situations including death and myocardial infarction. Although the risk factors, underlying pathophysiology and mechanisms of ST are not fully investigated, newer generation drug eluting stents, and high resolution intra-vascular imaging modalities are important for prevention of ST.