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December 15, 1999Blood

A Key Role of Adenosine Diphosphate in the Irreversible Platelet Aggregation Induced by the PAR1-Activating Peptide Through the Late Activation of Phosphoinositide 3-Kinase

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Authors

CTCatherine TrumelBPBernard PayrastreMPMonique Plantavid

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Trumel et al. (1999) studied this question.

synapsesocial.com/papers/69f41d04f3e494ed2b7d039fhttps://doi.org/10.1182/blood.v94.12.4156
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Released adenosine diphosphate stabilizes thrombin-induced human platelet aggregates1990 · 101 citations
  2. 2Coactivation of two different G protein-coupled receptors is essential for ADP-induced platelet aggregation1998 · 547 citations
  3. 3Reversible Translocation of Phosphoinositide 3-Kinase to the Cytoskeleton of ADP-aggregated Human Platelets Occurs Independently of Rho A and without Synthesis of Phosphatidylinositol (3,4)-Bisphosphate1997 · 29 citations
  4. 4An inherited bleeding disorder linked to a defective interaction between ADP and its receptor on platelets. Its influence on glycoprotein IIb-IIIa complex function.1995 · 202 citations
  5. 5D3 Phosphoinositides and Outside-in integrin Signaling by Glycoprotein IIb-IIIa Mediate Platelet Actin Assembly and Filopodial Extension Induced by Phorbol 12-Myristate 13-Acetate1996 · 132 citations