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Finds enhanced photodynamic immunotherapy efficacy in malignant tumors by reprogramming macrophages, indicating a novel approach.
cytotoxic T cells in tumor tissues to 2.85-fold of that in the PBS group while reducing the proportion of Treg cells to 0.86-fold. Collectively, this TAM-targeted reprogramming strategy provides a promising approach to overcome immunosuppressive TME and enhance the efficacy of photodynamic immunotherapy in malignant tumors.
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Shang et al. (2026) studied this question.
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