Why the study?
Do novel echocardiographic indices (MPI and PWT:LVC ratio) detect early myocardial involvement in asymptomatic patients with Chagas disease compared to seronegative controls?
Do novel echocardiographic indices (MPI and PWT:LVC ratio) detect early myocardial involvement in asymptomatic patients with Chagas disease compared to seronegative controls?
Simple Doppler echocardiographic parameters like the myocardial performance index and PWT:LVC ratio can detect early subclinical myocardial dysfunction in asymptomatic patients with Chagas disease.
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May aid early detection of subclinical involvement in asymptomatic Chagas; hypothesis-generating and requires prospective validation before clinical use.
Yacoub et al. (2003) studied this question.
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