What question did this study set out to answer?

To investigate the impact of hemoconcentration on muscle perfusion estimates in human calf muscle using near-infrared diffuse correlation spectroscopy (NIRS-DCS).

May 2, 20260 citations

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The Near-Infrared Diffuse Correlation Spectroscopy Muscle Perfusion Index in Human Calf Muscle - Accounting for Changes in Hemoconcentration.

MBMiles F. Bartlett KDK Austin Davis EEErin K. Englund

Key Points

To investigate the impact of hemoconcentration on muscle perfusion estimates in human calf muscle using near-infrared diffuse correlation spectroscopy (NIRS-DCS).
Utilized near-infrared diffuse correlation spectroscopy to measure muscle perfusion index.
Assessed changes during physiological conditions like ischemic reperfusion and exercise.
Compared NIRS-DCS findings with MRI results after adjusting for hemoconcentration.
Muscle perfusion estimates from NIRS-DCS aligned with MRI results when accounting for hemoconcentration.
Significant changes in muscle perfusion observed under physiological provocations, emphasizing measurement accuracy.

Abstract

were similar to MRI only after accounting for changes in hemoconcentration. Collectively, these results highlight the importance of accounting for changes in hemoconcentration when using NIRS-DCS to estimate changes in muscle perfusion during physiological provocations such as ischemic reperfusion and exercise.

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Cite This Study

Bartlett et al. (Thu,) studied this question.

synapsesocial.com/papers/69f594fc71405d493afffe40 https://doi.org/https://doi.org/10.1152/japplphysiol.01054.2025

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