Why the study?
Post-procedural AKI occurs in up to 20% of TAVR cases and is associated with increased mortality, especially in patients with pre-existing renal impairment where CKD also worsens clinical outcomes.
Does zero contrast transcatheter aortic valve replacement using a multimodality imaging approach prevent acute kidney injury in patients with severe aortic stenosis and renal dysfunction?
Does zero contrast transcatheter aortic valve replacement using a multimodality imaging approach prevent acute kidney injury in patients with severe aortic stenosis and renal dysfunction?
The text introduces a zero contrast TAVR approach using multimodality imaging for patients with renal dysfunction, but provides no results.
Answers are grounded in this paper and cite their sources.
Should not yet change TAVR practice in renal dysfunction; leaves open whether zero-contrast multimodality imaging prevents AKI.
Transcatheter aortic valve replacement (TAVR) is an established therapy for patients with severe, symptomatic aortic stenosis (AS). Post-procedural acute kidney injury (AKI) occurs in up to 20% of TAVR cases and is associated with increased mortality, particularly in patients with pre-existing chronic renal impairment.1,2 Chronic kidney disease (CKD) has been associated with worse clinical outcomes in patients treated with surgical AVRS1or TAVR.3 CKD promotes progression of AS4 and increases mortality in patients with severe AS.
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Dakroub et al. (2023) studied this question.
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