International travel during pregnancy represents a clinical challenge due to patient vulnerability and the scarcity of interventional studies in pregnant women. Although the second trimester is considered the safest period, every travel plan requires a thorough benefit-risk assessment. This article synthesizes obstetric issues, such as transportation safety, access to care, and the risks of complications inherent to the gestational age. It also addresses infectious risks in tropical regions, including malaria, dengue fever, and Zika virus, the severity of which is exacerbated by pregnancy. A specialized travel medicine consultation is essential to define personalized preventive measures (vaccination, vector protection, and food hygiene) and to facilitate informed decision-making.
Cordaillat et al. (2026) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: